Effect of Vitamins C & E on Aspirin Induced Gastric Mucosal Damage and Oxidative Stress
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چکیده
منابع مشابه
Effect of cimetidine and omeprazole on aspirin- and taurocholate-induced gastric mucosal damage in the rat.
The effect of varying doses of cimetidine and omeprazole, on acute gastric mucosal lesions produced by topical aspirin (200 mg/kg; 1 ml/100 g) in 0.175 M HCl or topical sodium taurocholate (40 mM; 1 ml/100 g) in 0.175 M HCl was studied in the pylorus ligated rat. Preliminary studies revealed dose dependent inhibition of acid secretion with both cimetidine and omeprazole. Intraperitoneal cimetid...
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Background—Oxidative stress is elevated in obesity, and may be a major mechanism for obesityrelated diseases. Methods—Nonsmokers (n=396) were randomized to 1000 mg/day vitamin C, 800 IU/day vitamin E, or placebo, for two months. Treatment effect was examined in multiple regression analyses using an intention-to-treat approach. Results—Vitamin C (p=0.001) and vitamin E (p=0.043) reduced plasma F...
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Background: The role of oxidative stress in endosulfan-induced reproductive toxicity has been implicated. This study was performed to evaluate the possible protective effect of vitamins E and C, against endosulfan-induced reproductive toxicity in rats. Methods: Fifty adult male Sprague–Dawley rats were randomly divided into five groups (n=10 each). The groups included a control receivin...
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Background & Objective: Endosulfan is one of the strong insecticides used in agriculture. This toxin is absorbed by inhalation and skin. Endosulfan has side effects such as infertility in men. This study surveys the effect of vitamins E and C on preventing the harmful effects of Endosulfan on spermatogenesis in adult male rats. Materials & Methods: Adult male rats (200-250 g) from Wistar...
متن کاملThe Protective Effect of Vitamins E and C on The Gastric Mucosal Barrier in Rats Irradiated With X-Rays
The protective effect of vitamins E and C on the gastric mucosal barrier in rats irradiated with X-rays was investigated. Thirty-two male Wistar Albino rats were used. The animals were divided into four groups and arranged of follows: the first group (n=8) was the sham group; the second group (n=8) was the control group which was irradiated with X-rays, the third group (n=8) to which vitamin C ...
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ژورنال
عنوان ژورنال: Current Research Journal of Biological Sciences
سال: 2014
ISSN: 2041-076X,2041-0778
DOI: 10.19026/crjbs.6.5495